![]() Se asocia al antecedente de migraña y hace plantear si se trata de un síntoma acompañante de la migraña, un aura migrañosa o de migraña oftalmopléjica. La midriasis benigna episódica se presenta predominantemente en mujeres jóvenes. Los estudios de neuroimagen (resonancia magnética cerebral) fueron normales. En estas, los episodios eran recidivantes (75%), de minutos de duración (75%) y asociaban visión borrosa (50%). Cuatro pacientes (57%) presentaban como antecedente migraña sin aura. La duración fue variable, desde minutos hasta 48 h. Los motivos de consulta fueron asimetría pupilar (n = 5) y visión borrosa (n = 2) de presentación fundamentalmente unilateral (n = 6). ![]() Todas eran mujeres, con edad media de 33 ± 10 años. Un total de 7 pacientes fueron diagnosticadas de MBE. Sujetos, material y métodosĭescribimos las características epidemiológicas y clínicas de los pacientes con MBE valorados en una UNO de un hospital terciario. La midriasis benigna episódica (MBE) es una causa aislada de asimetría pupilar intermitente, de fisiopatología no esclarecida y predominio en mujeres jóvenes migrañosas. En ausencia de síntomas acompañantes, suelen estar ocasionadas por procesos benignos. Suponen un reto diagnóstico por la variedad de procesos que pueden ocasionarla. Las anisocorias son un motivo de consulta relativamente frecuente en unidades de neuro-oftalmología (UNO). Imaging tests are not recommended in the absence of other accompanying symptoms, or in short-term episodes. Although BEM has unilateral predominance, there may be alternation of the affected eye or even bilateral impairment during the same episode, which makes us question the adequacy of the term to describe the process. It is frequently related to a previous history of migraine, and the specialist must consider if it is a concomitant symptom of common migraine, migraine with aura, or ophthalmoplegic migraine. DiscussionīEM appears predominantly in young women. ![]() The episodes in these 4 patients were recurrent (75%), often lasted for a few minutes (75%), and had associated blurred vision (50%). Four patients (57%) had a clinical history of migraine without aura. The duration of impairment varied from a few minutes to 48 hours. The patients presented with pupil asymmetry ( n = 5) and blurred vision ( n = 2), and 6 of the 7 patients had unilateral involvement. ResultsĪ total of 7 patients were diagnosed with BEM, all of them females, with a mean age of 33 ± 10 years. We describe the epidemiological and clinical characteristics of patients with BEM, assessed in a neuro-ophthalmology unit in a tertiary hospital. Benign episodic mydriasis (BEM) is an isolated cause of intermittent pupil asymmetry in which the pathophysiology is still not fully understood it is predominant in young women with migraine. In the absence of other accompanying symptoms, anisocorias are usually due to benign processes. They remain a diagnostic challenge for specialists as they may be due to several aetiological factors. Anisocorias are a relatively frequent reason for consultation in neuro-ophthalmology units.
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